William E. Donald, Elizabeth Cook, Nimmi P. Mohandas
Purpose This article synthesises contributions from the special issue “Fostering an inclusive and sustainable career ecosystem: empowering neurodivergent individuals and employees to thrive”. It reframes neurodivergence as a source of strength, while acknowledging the complex interplay between strengths and systemic challenges. The article advocates for evidence-informed strategies that promote inclusive and sustainable career pathways, emphasising the interaction between individual agency and structural change rather than commodifying neurodivergent talent as “superpowers”. Design/methodology/approach Guided by the sustainable career ecosystem theory, this article identifies five key principles derived from the nine contributions spanning four continents and seven countries. These principles are examined in relation to five United Nations Sustainable Development Goals, highlighting their global relevance and alignment with broader equity and sustainability agendas. The article concludes with a forward-looking research agenda that centres neurodivergent voices in shaping future scholarship and practice. Findings Five principles are essential for cultivating an inclusive and sustainable career ecosystem for neurodivergent individuals: championing neuroaffirming, strengths-based practice; recognising the interplay of diagnosis, identity and lifespan development; fostering neuroinclusive workplaces and leadership; addressing structural and societal barriers; and supporting sustainable outcomes and ecosystem impact. Together, these principles provide a cohesive framework for guiding inclusive career development and workplace transformation. Originality/value This article offers a novel synthesis of insights from the special issue, integrating current evidence into a coherent framework. It identifies actionable pathways for research, policy and practice to empower neurodivergent individuals. By articulating guiding principles, it provides a foundation for employers, career practitioners and neurodivergent employees to collaboratively develop neuroinclusive policies and foster systemic change.