Armin Kuellmer, Matthias Kandler, Sandra Nagl, Katharina Laubner, Maximilian Meyer-Steenbuck, Julius Mueller, Rafael Kaeser, Lukas Sturm, Jochen Seufert, Robert Thimme, Arthur Schmidt
In ASIRCTs with preoperative AHD ≤ 6 mm, both procedures improved function and radiology, but the addition of aMTT provided superior recovery of AHD, overhead motion, and strength. Augmenting an aLDTM tendon transfer with an aMTT may represent an effective strategy for optimizing outcomes in this challenging population.
Background and Aims Dumping syndrome (DS) and postbariatric hypoglycemia (PBH) represent common complications after Roux-en-Y gastric bypass (RYGB). Transoral outlet reduction (TORe) addresses the rapid passage of food through the gastrojejunal anastomosis which is central in pathophysiology. In this prospective multicenter study, technical feasibility and short-term clinical efficacy of a new clip-based endoscopic system (BARS) were evaluated. Methods Twenty-three consecutive patients at three centers in Germany were included. The primary endpoint was feasibility measured as reduction of anastomotic diameter and surface. Secondary endpoints included changes of the Dumping symptom score and glycaemia in modified oral glucose tolerance tests (mod. oGTT), anastomotic diameter, quality of life after 12 weeks and adverse events. Results The procedure was technically feasable in all cases. Median anastomotic diameter was reduced from 40 mm (IQR: 30-50) to 9 mm (IQR: 7-10); -77%) at baseline ( p < 0.001). At week 12, median Sigstad-Score decreased from 17,5 (IQR: 12.8-21.0) to 5 (IQR: 0-11; p < 0.001). Median anastomotic diameter was still reduced to 20 mm (IQR: 12-30; p = 0.004; -47%). Modified oGTT demonstrated abolished DS in 3 of 23 patients (13%) while no effect was seen in PBH at 12 weeks. Median BMI decreased from 30.6 kg/m 2 (IQR: 28-35.6) to 29.25 kg/m 2 (IQR: 26.7-33.4; p = 0.001). Quality of life (QoL) improved significantly in five of eight subcategories of the SF-36. Conclusion Clip-based anastomotic reduction for DS and PBH seems feasible, safe and showed significant improvements in Sigstad scores and QoL in short-term analysis.