Chen Xu, Quanyong Wang, Fene Hao, Lin Shi, Lu Zhu
Myoepithelial carcinoma (MC) is an exceptionally rare malignant neoplasm that predominantly originates in the salivary glands, with occurrence in visceral soft tissues being exceedingly sparse. Herein, we report the first documented case of primary MC of the gallbladder in a 57-year-old male. Although the patient exhibited non-specific clinical symptoms, radiological evaluations revealed distinctive features, including irregular wall thickening and progressive, non-uniform intraluminal enhancement. Histopathological and immunohistochemical analyses confirmed the diagnosis. Furthermore, we conducted a comprehensive review of the relevant literature, with a specific focus on the imaging features of MC. By consolidating these findings, this study aims to enhance clinical recognition, refine diagnostic accuracy, and provide a valuable reference for the management of this rare malignancy.