Transmission and Prevention of Uterine Dysfunction in Daughters of Dioxin Exposed Male Mice.
Breanna C Rose, Isabella R Land, Kevin G Osteen, Kaylon L Bruner-Tran
原始摘要(英文原文)· Original abstract
Daughters of women with endometriosis are known to be at increased risk of developing this disease. Using a mouse model, we demonstrate uterine dysfunction reminiscent of endometriosis patients can also be passed from the father to the daughter, potentially via an epigenetic pathway amenable to therapeutic intervention.