Plasma Microbial Cell-Free DNA Sequencing for the Diagnosis of Chronic Disseminated Candidiasis in Patients with Hematologic Malignancies.
Alejandro De La Hoz, Victor Kovac, Ann E Woolley, Nicolas C Issa, Alyssa Letourneau, Lindsey R Baden, Sarah P Hammond, Jessica S Little
原始摘要（英文原文）· Original abstract
Diagnosis of chronic disseminated candidiasis (CDC) is frequently delayed because clinical manifestations are nonspecific and conventional diagnostic tests have limited sensitivity. We describe a series of 19 CDC cases in which plasma microbial cell-free DNA sequencing was performed due to diagnostic uncertainty. Results influenced antifungal management in most cases.
Plasma Microbial Cell-Free DNA Sequencing for the Diagnosis of Chronic Disseminated Candidiasis in Patients with Hematologic Malignancies. — 科研速览 Science Skim