◆ Journal of the Pediatric Infectious Diseases Society2026-08-29
The role of 1-3-beta-D-glucan in predicting Pneumocystis jirovecii Pneumonia in Immunocompromised Children.
Markus Keldorfer, Raphael Ulreich, Johann Martensen, Patrick Faudon, Klaus Pfurtscheller, Siegfried Rödl, Robert Krause, Karl Dichtl, Volker Strenger, Stefan Hatzl
原始摘要(英文原文)· Original abstract
Serum 1,3-β-D-glucan (BDG) showed high negative predictive value (~99%) for Pneumocystis jirovecii pneumonia (PJP) in 106 non-HIV immunocompromised children, but modest positive predictive value at low prevalence. These exploratory findings suggest BDG may help exclude PJP, pending prospective validation.