Giovanni Abrahão Salum, Carina de Giusti, Laila Souza, Juliana Juk, Rafaela Alkmin da Costa, Luisa Sugaya, Arthur Caye, André Simioni, Paula B. Rocha, Gisele Gus Manfro, Lucas Toshio Ito, Francisco Da Silva, Igor Duarte, Nathália Bianchini Esper, Maurício Anés, Rodolfo Furlan Damiano, Theodore D Satterthwaite, Carolina Muniz Carvalho, Patrícia Bado, Maurício Scopel Hoffmann, Julia Schäfer, C Casella, Sara Evans‐Lacko, Carolina Ziebold, Rudi Rocha, André Zugman, Andrea Parolin Jackowski, Ary Gadelha, Marcelo Q. Hoexter, Clarice S. Madruga, Rodrigo Grassi‐Oliveira, Annamaria Cattaneo, Audrey R. Tyrka, Tomáš Paus, Daniel S. Pine, Ellen Leibenluft, Argyris Stringaris, Kathleen Merikangas, Michael P. Milham, Alexandre R. Franco, Marcos Santoro, João Ricardo Sato, Vanessa Ota, Guilherme V. Polanczyk, Jair de Jesus Mari, Rodrigo A. Bressan, Eurı́pedes Constantino Miguel, Luís Augusto Rohde, Síntia Belangero, Pedro Mário Pan
The Brazilian High-Risk Cohort for Mental Health Conditions (BHRC), formerly the High-Risk Cohort Study for Psychiatric Disorders in Childhood (HRC) [1], was established to advance the understanding of the developmental trajectories of pediatric mental health conditions by integrating information about behaviors, genes, environments, and brain development. The BHRC has an accelerated school-based longitudinal design in which children born between 1996 and 2004 were recruited at school in 2009 and 2010 and assessed every 2–4 years. The BHRC is one of the few population neuroscience studies from a middle-income country, integrating in-depth clinical assessments with data on environmental influences, genetics, imaging, cognition, and ecological momentary assessment (EMA), among others [2]. The cohort was established as a collaborative effort among three Brazilian universities: Universidade de São Paulo, Universidade Federal do Rio Grande do Sul, and Universidade Federal de São Paulo. This was possible through a networking grant from the Brazilian Science and Technology Ministry, which created the National Institute of Developmental Psychiatry for Children and Adolescents (in Portuguese, “Instituto Nacional de Psiquiatria do Desenvolvimento para a Infância e Adolescência”). Participants were recruited at state-funded schools of two Brazilian metropolitan areas: Porto Alegre (South, 1.5 million inhabitants, metropolitan area 4.4 million inhabitants) and São Paulo (Southeast, 11.4 million inhabitants, metropolitan area 22.8 million inhabitants).