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◆ Clinical infectious diseases : an official publication of the Infectious Diseases Society of America2026-09-25

Glecaprevir/Pibrentasvir Concentrations in the Breastmilk of Lactating Women.

L Madeline McCrary, Hideji Fujiwara, John Robinson, Jeannie Kelly, Megan R Curtis, Michael J Durkin, Tracey Habrock-Bach, Jeffrey P Henderson, Laura R Marks

原始摘要(英文原文)· Original abstract
In this prospective pharmacokinetic study of women undergoing chronic hepatitis C virus treatment with glecaprevir/pibrentasvir, the mean glecaprevir and pibrentasvir concentrations in breastmilk were 0.63% and 4.23% of maternal plasma concentrations, with a mean relative infant dose of 0.02% and 0.06%, respectively.
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Glecaprevir/Pibrentasvir Concentrations in the Breastmilk of Lactating Women. — 科研速览 Science Skim