Triglyceride Storage is Upregulated in Different Mouse Non-Melanoma Skin Cancer Cell Lines.

Links between tumorigenesis and lipid metabolism have been observed in various cancers, but whether lipid metabolism is altered in skin cancers is not well understood. Here we show that two different mouse skin cancer cell lines accumulate more triglycerides when compared to normal keratinocytes. This suggests that lipid metabolism is altered in mouse skin cancer tumor progression and may have implications for the regulation of lipid metabolism in non-melanoma skin cancer in humans.