Abstract Objectives This study aimed to assess farmers’ knowledge, attitudes, and practices regarding pesticide use and the use of personal protective equipment (PPE), as well as the health issues associated with exposure and improper handling. Methods Data were collected through face-to-face interviews using structured questionnaires. Results The results showed that none of the participants were aware of the biohazards associated with pesticide exposure, proper application methods, appropriate post-application practices, or the safe disposal of empty pesticide containers. Consequently, farmers experienced various health issues following pesticide use. Conclusion Continuous education and training programs are essential to increase farmers’ awareness of pesticide-related biohazards, correct application methods, and proper disposal techniques.