CMS Collaboration
Combined measurements of Higgs boson production and decay rates are reported, representing the most comprehensive study performed by the CMS Collaboration to date. The included analyses use proton-proton collision data recorded by the CMS experiment atfrom 2016 to 2018, corresponding to an integrated luminosity of 138 fb. The statistical combination is based on analyses that measure the following decay channels:,,,,,, and. Information in the events from each decay channel is used to target multiple Higgs boson production processes. Searches for invisible Higgs boson decays are also considered, as well as an analysis that measures off-shell Higgs boson production in the() decay channel. The best fit inclusive signal yield is measured to betimes the standard model (SM) expectation, for a Higgs boson mass of 125.38 GeV. Measurements in kinematic regions defined by the simplified template cross section framework are also provided, as well as interpretations in the coupling modifier and SM effective field theory frameworks. The coupling modifier interpretation is further used to place constraints on various two-Higgs-doublet models. The results show good compatibility with the SM predictions for the majority of the measured parameters.