Pengfei Yu, Xian-liang Zhao, Luyi Chen, Zhihao Zhou, Chang Zhao
Abstract An efficient dehalogenation reaction of α-substituted halogenated heterocycles catalyzed by Pd/C with triethylsilane (TES) was developed. This study explores the catalytic dehalogenation of N-heteroaryl halides using a Pd/C-K2CO3 system, with TES serving as the hydrogen source under air conditions (air and moisture). The reaction conditions are compatible with various functional groups with good to excellent yields.