Jiangtao Lin, Mingqian Zhou, Ziyang Li, Jiang Duan, Xiaoyu Liu, Y P Wang, Chao Shu
the photoinduced radical cyclization of ketone-derived pro-aromatic dihydroquinazolinones. This system operates under very mild conditions and showcases a broad substrate scope with excellent functional group tolerance (over 50 examples). Its gram-scale preparation and late-stage transformations emphasize its potential in drug discovery. A possible mechanism has been proposed based on mechanistic studies.