Design, synthesis and anticonvulsant evaluation of novel 2,4,5-trichlorobenzenesulfonate-based dihydrothiazoles supported by <i>in vivo</i> and <i>in silico</i> studies
Faiqa Noreen, Muhammad Iftikhar Shoukat, Imran Imran, Farhan Siddique, Sumaira Nadeem, Mostafa A. Ismail, Xianliang Zhao, Magdi E. A. Zaki, Sobhi M. Gomha, Zahid Shafiq
原始摘要（英文原文）· Original abstract
findings, compound 3c emerged as the most important candidate, demonstrating superior anti convulsant activity across multiple seizure models. These results underscore the capability of the newly synthesized 2, 4, 5-trichlorobenzenesulfonate based dihydrothiazoles as promising scaffolds for the development of new antiepileptic drugs.