Shengping Zhou, Zongli Xiong, Yuqiao Zhou, Wenling Qin, Weijun Yao, Zhen Wang
A SaBox/Cu(II)-catalyzed enantioselective Claisen rearrangement of a broad spectrum of 2-allyloxycyclohex-2-en-1-ones, 3-allyloxy-4H-chromenones, and their structural analogues has been established. The current method enables the stereoselective construction of enantioenriched 2-hydroxy-3-allylcyclohex-2-en-1-one and 2-allyl-3-hydroxy-4H-chromen-4-one scaffolds, delivering the corresponding chiral derivatives with moderate to good yields and ee values.