Chiral cyclopropenimine-catalyzed enantioselective reactions: a mini-review.

Since the first chiral cylcopropenimine (CPI) was reported by Lambert and colleagues in 2012, this type of chiral organosuperbase has been used to catalyze asymmetric Michael reactions, Mannich reactions, and [3 + 2] cyclization reactions in high to excellent yields and stereoselectivities. In this mini-review, we have provided a comprehensive overview of chiral cyclopropenimines, including their structural features, preparation, versatility in asymmetric synthesis, and mechanistic studies. Furthermore, we have offered a perspective on the future development of this new class of chiral organosuperbases.