◆ Chemical communications (Cambridge, England)2026-08-18
Base-promoted dearomatization/1,6-addition of α-haloketones: synthesis of α-azido-α,α-diaryl ketones.
Ze-Yu Su, Bo Lu, Yi-Rui Zhang, Jun-Hui Luo, Xue Huang, Bao Qiong Li, Ya-Jie Chen, Xiang-Zhi Zhang
原始摘要（英文原文）· Original abstract
We report an unprecedented tandem process involving a dearomatization/1,6-conjugate addition sequence that enables the α-azidation of ketones. This transformation operates at room temperature, exhibits excellent chemo- and regioselectivity, and requires no external oxidants or metal catalysts.