A carbon paper-confined strategy mediated by deep eutectic solvents is proposed for the rational construction of 2D high-entropy (CrMnFeCoNi)3O4@CP electrodes toward efficient OER. Integrating entropy modulation and interfacial enhancement, the monolithic electrode achieves an overpotential of 369 mV at 1 A cm-2 and durable stability over 55 hours.