Se-catalyzed enantioselective lactamization enabled by a <i>N</i> -fluorosulfonyl group: total synthesis of diaporisoindole A

-(fluorosulfonyl)carboxamides as versatile and reactive substrates that overcome this limitation, as demonstrated by a selenium-catalyzed enantioselective lactamization, facile product derivatization, and application to the total synthesis of diaporisoindole A. To further showcase their synthetic potential, we briefly demonstrate their applicability in racemic iodo- and hydro-lactamizations.