Fast-switching pH-responsive biomimetic ion channels with bidirectional gating control
Wen Zhao, Linlin Shi, Juan Chen, Jingjing Ma, Qingqing Lv, Yonghui Sun, Nan Lv, Xiaoyu Chang, Pengyang Xin
原始摘要(英文原文)· Original abstract
conformational changes, mirroring that of natural ASICs. Stopped-flow experiments further demonstrated that this biomimetic system exhibits millisecond-timescale gating kinetics under pH modulation, achieving response rates comparable to those of natural ion channels.