Synthesis and separation of two stereoisomers of deuterated tetrasubstituted allylic alcohols <i>via</i> consecutive dual 1,2-metallate shifts

consecutive dual 1,2-metallate shifts, achieving efficient construction of both isomeric deuterated allylic alcohols without the requirement for condition optimization or the selection of special reagents and substrates upon oxidation. And the method features quantitative deuterium incorporation (>99%), broad substrate scope, and direct access to pharmaceutically relevant scaffolds under mild conditions.