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◆ RSC Advances2026-01-01· Apoptosis

Targeting cell cycle and apoptotic pathways with newly synthesized diselenide-linked imidazolone analogues with strong CDK6-targeting potential

Marwa Abdel‐Motaal, Saad Shaaban, Samia S. Hawas, Asma M. Elsharif, Marwa Sharaky, Fatema Suliman Alatawi, Mohamed E. Eissa, Arwa Omar Al Khatib, Prof. Hany M. Abd El-Lateef, Medhat Asem, Ahmed A. Al-Karmalawy

原始摘要(英文原文)· Original abstract
< 10 µM), highlighting the broader therapeutic relevance of this scaffold. Collectively, these data position 6g as a compelling multi-target anticancer lead that integrates apoptosis induction, cell-cycle regulation, and angiogenesis suppression-supporting its potential for development as a next-generation broad-spectrum anticancer agent.
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Targeting cell cycle and apoptotic pathways with newly synthesized diselenide-linked imidazolone analogues with strong CDK6-targeting potential — 科研速览 Science Skim