Wanyan Wu, Yan Guo, Lidan Deng, Wenwu Gong, Shunyu Hu, F. Z. Liu, Chang-ye Hui
> 0.98) with negligible matrix effects, enabling direct colorimetric quantification of culture supernatants. Notably, metabolic burden from pigment synthesis dominated the dose-response profile rather than MeHg cytotoxicity. This biosensor offers a cost-effective alternative for screening MeHg in environmental water, with detection limits that far exceed WHO drinking water guidelines and a potential for high-throughput environmental monitoring.