Polysubstituted bicyclo-[2.1.1]-hexanes as benzene isosteres for medicinal chemistry
Eugenio Roà, Quentin Lefebvre
原始摘要（英文原文）· Original abstract
This comprehensive review describes the methodologies reported between 2020 and early 2025 for the synthesis of (hetero)bicyclo[2.1.1]hexane derivatives, organised by mechanisms and the exit vectors achieved.