<i>EV-Blade</i> : an automated centrifugal-pneumatic cartridge for size- and affinity-based exosome isolation from whole blood

for use in cancer patient risk stratification. The system presented herein represents a significant advancement in exosome purification, offering a robust and automated platform for liquid biopsy-based cancer research and clinical applications. This innovation holds promise for cancer diagnosis, prognosis, and monitoring through non-invasive biomarkers.