Scalable mechanochemical synthesis of amides using bead milling technology
Pietro Caboni, Andrea Porcheddu, Sándor B. Ötvös, C. Oliver Kappe
原始摘要（英文原文）· Original abstract
A scalable protocol for mechanochemical amide bond formation was developed using a commercially available agitator bead mill without requiring reagent excess, added base or large quantities of organic solvent, significantly reducing waste generation.