Sulfated polysaccharides from sea cucumber mitigate acetaminophen-induced acute liver injury in mice <i>via</i> citraconic acid-mediated inhibition of oxidative stress
Jiacheng Cheng, Weiyun Zheng, Jiayi Yan, Shuang Song, Chunqing Ai
原始摘要(英文原文)· Original abstract
Sea cucumber sulfated polysaccharides alleviate acetaminophen - induced liver injury by modulating gut microbiota to elevate citraconic acid, which activates hepatic Nrf2 to reduce oxidative stress, as validated in vivo and in t-BHP-treated cells.