Lewis acid-switched regiodivergent <i>N</i> <sup>1</sup> / <i>N</i> <sup>2</sup> -alkylation of ben-zotriazoles with α-hydroxyl diazo compounds
Jingjing Jiang, Jinghan Zhang, Nan Huang, H. Eric Xu, X. Liu, Jiayin Li, Xinlong Zhou, Jingjing Zhao, Pan Li
原始摘要(英文原文)· Original abstract
A Lewis acid-switching strategy that enables programmable selectivity between kinetically controlled N 1 -alkylation and thermodynamically favored N 2 -alkylation using β-hydroxy-α-diazo carbonyls as versatile electrophiles has been disclosed.