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◆ Chemical Communications2026-01-01· Diazo

Lewis acid-switched regiodivergent <i>N</i> <sup>1</sup> / <i>N</i> <sup>2</sup> -alkylation of ben-zotriazoles with α-hydroxyl diazo compounds

Jingjing Jiang, Jinghan Zhang, Nan Huang, H. Eric Xu, X. Liu, Jiayin Li, Xinlong Zhou, Jingjing Zhao, Pan Li

原始摘要(英文原文)· Original abstract
A Lewis acid-switching strategy that enables programmable selectivity between kinetically controlled N 1 -alkylation and thermodynamically favored N 2 -alkylation using β-hydroxy-α-diazo carbonyls as versatile electrophiles has been disclosed.
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Lewis acid-switched regiodivergent <i>N</i> <sup>1</sup> / <i>N</i> <sup>2</sup> -alkylation of ben-zotriazoles with α-hydroxyl diazo compounds — 科研速览 Science Skim