Imaging and Characterization of Ganglioside-Induced Amyloid Fibril Formation.

High-density nanoclusters of gangliosides in membrane rafts interact with amyloid β protein (Aβ), which induces toxic Aβ aggregation. This chapter describes how to generate, detect, and assess the Aβ aggregates induced by ganglioside-containing liposomes and planar lipid bilayers.