Timothy R. Huerta, Christopher W. Bartlett, Gabriel Alain, Thomas Bentley, Carol R. Bradford, John F. P. Bridges, Arnab Chakravarti, Alexander A. Farag, Cynthia A. Gerhardt, Tyler Gorham, Shaun J. Grannis, Yungui Huang, Julie A. Johnson, Nina V. Kraguljac, Lang Li, Qin Ma, Puneet Mathur, Mary Z. Mays, Ann Scheck McAlearney, Eneida A. Mendonça, Sayoko E. Moroi, Xia Ning, Colin Odden, Lauren Phelps, William E. Smoyer, Robert Strouse, Curtis Walker, Ping Zhang, Dukagjin Blakaj
The concept of a Learning Health System (LHS) has been widely discussed in academic literature, yet its practical implementation remains a challenge. This paper describes the institutional journey, leadership structure, data governance policies, and technical innovations that together support a scalable and sustainable Research-Oriented LHS. Additionally, we propose an expanded data vision that aligns with interdisciplinary and translational research needs. Supplementary materials provide technical details for those interested in implementing such a model.