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◆ Nature Synthesis2025-12-08· Reagent

Mechanochemical synthesis of organosodium compounds through direct sodiation of organic halides

Keisuke Kondo, Matthew Lowe, Nathan Davison, Paul G. Waddell, Roly J. Armstrong, Erli Lu, Koji Kubota, Hajime Ito

原始摘要(英文原文)· Original abstract
A mechanochemical protocol for the direct synthesis of organosodium compounds is developed using cheap and shelf-stable sodium lumps and readily available organic halides under bulk, solvent-free conditions. This approach allows for the generation of an array of organosodium compounds in minutes, without special precautions against moisture or temperature control.
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