ProPE expands the prime editing window and enhances gene editing efficiency where prime editing is inefficient
Sarah Krausz, Dorottya Anna Simon, Zsuzsa Bartos, Zsuzsanna Biczók, Éva Varga, Krisztina Huszár, Péter István Kulcsár, András Tálas, Zoltán Ligeti, Ervin Welker
原始摘要（英文原文）· Original abstract
Prime editing is a CRISPR methodology whose efficiency declines with distance from the target sequence. Here the authors demonstrate prime editing with prolonged editing window, proPE, which extends the editing distance, enabling the use of prime editing for therapeutic interventions.