Jasmine Chiat Ling Ong, Yilin Ning, Mingxuan Liu, Yian Ma, Liang Zhao, Kuldev Singh, Robert T. Chang, Silke Vogel, John C. W. Lim, I Leng Tan, Oscar Freyer, Stephen Gilbert, Danielle S. Bitterman, Xiaoxuan Liu, Alastair K. Denniston, Nan Liu
The integration of generative AI (GenAI) and large language models (LLMs) in healthcare presents both unprecedented opportunities and challenges, necessitating innovative regulatory approaches. In this perspective, we discuss the risks of GenAI and LLM-based medical devices, the limitations of current medical device regulation frameworks when applied to GenAI or LLMs, and advocate for global collaboration in regulatory science research through engaging multidisciplinary expertise and focusing on the needs of diverse populations.