Yuliana Tan, Anika Liu, Emily Larkin, Revati Wani, Alec Dick, Stefano Patassini, Patrik Erlmann
Senescence is a key pathomechanism across chronic diseases but also highly heterogeneous. In this study, we demonstrate that high-content imaging and transcriptomics can jointly shed light on senescence in vitro, distinguishing replicative and chemically induced senescence, differentiating from quiescence and characterizing the senolytic response.