Ligand engineering tailors hydrophobic microenvironments for efficient electrocatalytic oxidation of fatty alcohol

, achieving a threefold higher production rate and significantly improved Faradaic efficiency (84.7% versus 30.8%). The octanoic acid production rate is competitive with that of state-of-the-art thermocatalytic aerobic oxidation. This work highlights a general design principle for hydrophobic microenvironment to overcome mass transport barriers in organic electrocatalysis, demonstrating its potential for practical applications.