Practical Ni-Catalyzed Synthesis of Allylic Boronates.

Two nickel-catalyzed protocols for the borylation of allylic acetates have been developed, enabling direct and efficient access to allylic boronates under operationally simple conditions. Both transformations are setup on the benchtop, employing commercially available Ni catalysts in combination with readily accessible boron reagents. The methods exhibit broad functional group tolerance and substrate generality, as demonstrated across 28 examples, delivering the corresponding allylic boronates in isolated yields of up to 93%. Notably, gram-scale reactions proceed with comparable efficiency, underscoring the scalability and synthetic utility of the approach.