Emil Durukan, Christian Fuglesang S Jensen, Kristoffer Grundtvig Skaarup, Mikkel Fode
Erectile dysfunction (ED) is a prevalent condition, recognized as a sentinel marker of cardiovascular disease. Epidemiological and mechanistic evidence link ED to cardiovascular risk, with a prominent role of low-grade inflammation, endothelial dysfunction and atherosclerosis. ED might serve as an early indicator of subclinical vascular disease, and diagnostic strategies, including coronary artery calcium scoring and echocardiography, can be considered to enhance risk stratification. Management approaches that integrate sexual and cardiometabolic health are beneficial to improve care in this at-risk population.