Common factors in altered states: Understanding psychedelic therapy through the lens of Grawe’s general change mechanisms.

-an empirically grounded framework of psychotherapeutic "common factors" that emphasizes therapeutic experiences and change processes. Drawing on extensive evidence from psychedelic research, we argue that the efficacy of psychedelic therapy is ultimately mediated by the same five general change mechanisms that underlie all effective psychotherapies: (1) resource activation, (2) therapeutic relationship, (3) problem actuation, (4) clarification, and (5) mastery. Implications for clinical practice, training, and future research are discussed. (PsycInfo Database Record (c) 2025 APA, all rights reserved).