A pilot randomized clinical trial evaluating the feasibility, acceptability, and preliminary efficacy of a cognitive–behavioral therapy adjunct to support benzodiazepine tapering among primary care patients coprescribed benzodiazepines and opioids.

OBJECTIVE: Benzodiazepine (BZ) use concerns have escalated in the wake of the opioid crisis, including increased overdose risk from co-use of BZ and opioids. Research evidence to inform clinical management of this issue is currently lacking. METHOD: = 20). RESULTS: = 0.33), with similar findings for pain catastrophizing and anxiety sensitivity. CONCLUSIONS: The promising effect sizes obtained, along with evidence of adequate feasibility and acceptability, encourage further examination of the BZT + CBT approach. (PsycInfo Database Record (c) 2026 APA, all rights reserved).