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◆ ACS Central Science2026-02-02· Key (lock)

From Prompt to Drug: Toward Pharmaceutical Superintelligence

Alex Zhavoronkov, David Gennert, Jiye Shi

原始摘要(英文原文)· Original abstract
The convergence of generative artificial intelligence (AI) platforms and automated laboratory systems is ushering in a new era of drug discovery, in which a plain-language prompt can initiate a fully autonomous, end-to-end drug development program. This article explores the recent evolution of AI technologies and presents a "prompt-to-drug" pipeline, where AI not only generates novel hypotheses and designs optimized drug candidates but also orchestrates synthesis, validation, and clinical planning in a closed-loop system. By highlighting key breakthroughs, case studies, and the technological infrastructure required for this paradigm shift, we outline a vision for scalable, efficient, and unbiased drug discovery.
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From Prompt to Drug: Toward Pharmaceutical Superintelligence — 科研速览 Science Skim