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◆ Organic letters2026-09-04

Conversion of Phenyliodine(III) Dicarboxylates to Carbonyl Compounds via Hantzsch Ester-Enabled Decarboxylative Oxygenation.

Qingye Fang, Jiaxin He, Kaiyue Yang, Dan Xiao, Yilin Wang, Zhijian Wang, Yunfei Du, Kang Zhao

原始摘要(英文原文)· Original abstract
A series of phenyliodine(III) dicarboxylates, readily formed in situ from the reaction of carboxylic acids with PhIO, could undergo Hantzsch ester (HE)-enabled decarboxylative oxygenation with O2 from air as the oxidant to give a wide variety of the corresponding aldehydes and ketones. Mechanistic studies provide strong evidence for hydroperoxides as key intermediates in this transformation.
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Conversion of Phenyliodine(III) Dicarboxylates to Carbonyl Compounds via Hantzsch Ester-Enabled Decarboxylative Oxygenation. — 科研速览 Science Skim