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◆ Organic Letters2026-03-16· Chemistry

Sustainable Synthesis of <i>N</i> -Substituted Pyrroles via Fe-Catalyzed One-Pot Multicomponent Reaction

Santana Chakraborty, Arijit Singha Mohapatra, Nanda D. Paul

原始摘要(英文原文)· Original abstract
-substituted pyrroles from readily accessible feedstocks, such as alcohols, diols, and amines, catalyzed by a well-defined Fe(II)-catalyst featuring a redox-active azo-aromatic-1,10-phenanthroline-based ligand. Compared to existing approaches, this protocol enables access to diverse pyrrole derivatives, including penta-substituted pyrroles and complex polycyclic frameworks in good yields with improved atom economy and broad functional-group tolerance.
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