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◆ The Journal of organic chemistry2026-08-21

Pd-Catalyzed Regioselective Phenoxyl-Arylation of Ynamides: An Access to Tetrasubstituted Ketene N,O-Acetals.

Jianjun Wang, Xiaoqi Li, Wei Liu, Xiao Zhang, Shiwei Zhang, Yian Shi

原始摘要(英文原文)· Original abstract
This work describes an efficient Pd-catalyzed regioselective phenoxyl-arylation of ynamides with aryl iodides and phenols, providing a wide variety of tetrasubstituted ketene N,O-acetals in up to 99% yield. The reaction likely involves a syn-oxypalladation of the ynamide.
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Pd-Catalyzed Regioselective Phenoxyl-Arylation of Ynamides: An Access to Tetrasubstituted Ketene N,O-Acetals. — 科研速览 Science Skim