CoFe2O4-Catalyzed Three-Component One-Pot Synthesis of (2-Imino)-1,3-oxathioles.

A convenient, one-pot synthesis of (2-imino)-1,3-oxathioles derivatives from readily available nitrobenzene, 2-naphthol, and carbon disulfide is developed, using magnetically separable CoFe2O4 as a heterogeneous catalyst. This three-component protocol enables efficient construction of the target heterocycles and allows for easy catalyst recovery and reuse via an external magnet. A range of substrates are well tolerated, affording the corresponding products in good yields.