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◆ The Journal of Organic Chemistry2026-01-21· Hydroxamic acid

Visible Light-Induced Cyclization of <i>N</i> -Arylmethacrylohydrazides and Hydroxamic Acid Derivatives toward δ-Amidoalkylated Pyrazol-5-ones via 1,5-Hydrogen Atom Transfer

Yangjian Cheng, Guocheng Yin, Jin-Tao Yu

一句话结论

-arylmethacrylohydrazides and hydroxamic acid derivatives for the synthesis of pyrazol-5-ones via 1,5-hydrogen atom transfer was developed.

原始摘要(原文)
-arylmethacrylohydrazides and hydroxamic acid derivatives for the synthesis of pyrazol-5-ones via 1,5-hydrogen atom transfer was developed. A series of pyrazol-5-ones was obtained in good yield with a broad substrate scope and excellent functional group compatibility. The procedure was also applied to the late-stage modification of natural products and drug molecules.
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Visible Light-Induced Cyclization of <i>N</i> -Arylmethacrylohydrazides and Hydroxamic Acid Derivatives toward δ-Amidoalkylated Pyrazol-5-ones via 1,5-Hydrogen Atom Transfer — 科研速览 Science Skim