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◆ The Journal of Organic Chemistry2026-01-14· Annulation

Synthesis of 2-Thioxo-1,3-benzothiazin-4-one by PPh <sub>3</sub> -Promoted Desulfurative [4 + 2] Annulation

Chuan‐Chuan Wang, MENG-RU REN, Q. H. Wang, Shu-Yan Wu, Hong Zhang, Zhi-Hao Wang, Yao-Jie Xue, Yajing Chen

原始摘要(英文原文)· Original abstract
An efficient construction of 2-thioxo-1,3-benzothiazin-4-ones has been developed via a PPh 3 -promoted desulfurative [4 + 2] annulation between benzo[ c ][1,2]dithiol-3-ones and isothiocyanates. This strategy is characterized by its mild reaction conditions, operational simplicity, excellent yields, wide functional group tolerance, accessible scalability, and practical transformations.
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Synthesis of 2-Thioxo-1,3-benzothiazin-4-one by PPh <sub>3</sub> -Promoted Desulfurative [4 + 2] Annulation — 科研速览 Science Skim