Emergence of a novel genotype of extensively drug-resistant <i>Shigella sonnei</i> carrying <i>blaDHA-1</i> in diverse patient populations, Los Angeles, 2024–2025
Shekina Gonzalez-Ferrer, Bennett Shaw, Lilian Fung, Raphael J. Landovitz, Daniel Z. Uslan, Shangxin Yang
原始摘要（英文原文）· Original abstract
Abstract Extensively drug-resistant (XDR) Shigella is a public health threat, historically linked to blaCTX-M-15 gene in sexually transmitted cases. We describe a novel XDR S. sonnei carrying an AmpC-type blaDHA-1 gene from two unrelated cases with unknown transmission route; whole-genome sequencing revealed close genetic relatedness, signaling broader community spread.
Emergence of a novel genotype of extensively drug-resistant <i>Shigella sonnei</i> carrying <i>blaDHA-1</i> in diverse patient populations, Los Angeles, 2024–2025 — 科研速览 Science Skim