Malanka Lankaputhra, Federica Caldaroni, Melissa Gy Lee
An 18-year-old woman with truncus arteriosus presented with septic shock due to methicillin-sensitive Staphylococcus aureus infective endocarditis of her right-ventricle-to-pulmonary-artery (RV-PA) conduit requiring urgent conduit replacement and a prolonged admission complicated by acute respiratory distress syndrome and significant deconditioning. She had three separate presentations to external medical practitioners in the week preceding admission. This case underscores the complexity of managing infective endocarditis in patients with congenital heart disease and the importance of early referral to a specialist congenital centre.