Jyai Allen, Jenny Gamble, Sarah Hay, Caitlyn Atkinson, Lukman Thalib
Future research should prioritise adequately powered, randomised studies to definitively establish causal effects and inform clinical practice.
PROBLEM: Pregnant adolescents are a vulnerable group who face barriers to accessible, acceptable, and comprehensive maternity care, contributing to poorer perinatal outcomes.
BACKGROUND: There is a gap in the evidence on maternity models of care for young women. Three relevant quantitative reviews were published (2012, 2018, 2023). Two reviews examined antenatal interventions for the population without conducting quantitative data synthesis. Two reviews included a mix of interventions to address social determinants of health which were not limited to the antenatal period.
AIM: To determine the risk of preterm birth for young women aged ≤ 25 years in innovative models of care with a midwife, compared with routine care.
METHOD: This review synthesises evidence from randomised controlled and observational studies that met inclusion criteria. Searches were conducted across four databases from inception to November 2025. Meta-analysis was conducted where sufficient data were available; otherwise, narrative synthesis was used. Researchers assessed methodological quality and risk of bias; publication bias; certainty of evidence; and heterogeneity.
FINDINGS: From 2389 records, two randomised controlled trials and 10 observational studies involving 6227 participants were included. Overall, innovative models significantly lowered the risk of preterm birth (RR:0.62, 95% CI: 0.49-0.80; I2 =44.3%).
DISCUSSION: Innovative models of care that include a midwife, designed to meet the specific needs of young women, may reduce preterm birth. This should be interpreted with caution due to potential confounding in non-randomised studies.
CONCLUSION: Future research should prioritise adequately powered, randomised studies to definitively establish causal effects and inform clinical practice.