Exercise metabolism: MoTrPAC-ing the liver in endurance exercise.

The Molecular Transducers of Physical Activity Consortium (MoTrPAC) is a comprehensive research program designed to elucidate the molecular pathways induced by exercise. As a continuation of MoTrPAC studies, Kelty et al. report dynamic and sex-dimorphic molecular responses in rats through which endurance exercise regulates liver metabolism to maintain tissue homeostasis.